An endometrium is receptive when it is ready for embryo implantation. This occurs around days 19-21 in each menstrual cycle of a fertile woman. This period of receptivity is what we call the window of implantation.
This is why it is recommended to assess the endometrium in order to determine the optimal day for embryo transfer.
The ERA test requires an endometrial biopsy that should be carried out on day LH+7 (natural cycle) or day P+5 (HRT cycle). This biopsy is quickly and easily taken by a gynecologist in their consultation room and sent to Igenomix for testing.
The ERA test analyzes the expression levels of 248 genes linked to the status of endometrial receptivity, using RNA sequencing taken from the endometrial tissue.
3 in every 10 patients have a displaced WOI. The ERA is able to predict receptivity and recommend a transfer within a 24hr shift in the WOI.
The Endometrial Receptivity Analysis (ERA®) has been designed, developed and patented by IGENOMIX (PCT/ES2009/000386).
Ruiz-Alonso et al, Fertil Steril. 2013
Clemente-Ciscar et al, 2018, submitted
The ERA test is performed with Next Generation Sequencing (NGS) technology
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ERA tests performed